R01-CA68212-11 Progress Report Publications

  1. A. Marintchev, G. Wagner: Translation initiation: structures, mechanisms and evolution, Quart. Rev. Biophys, 37, 197-284 (2005). PMID: 16194295 Full Text

  2. T. von der Haar, Y. Oku, M. Ptushkina, N. Moerke, G. Wagner, J. D. Gross, J. E.G. McCarthy : Folding transitions during assembly of the eukaryotic mRNA cap-binding complex, J. Mol. Biol., 356, 982-992 (2006). PMID: 16405910 Full Text

  3. Y. Yamamoto, C. R. Singh, A. Marintchev, N. S. Hall, E. M. Hannig, G. Wagner, and K. Asano: The eukaryotic initiation factor (eIF) 5 HEAT domain mediates multifactor assembly and scanning with distinct interfaces to eIF1, eIF2, eIF3, and eIF4G., PNAS, 102, 16164-16169 (2005). PMID: 16254050 Full Text

  4. A. Natarajan, N. Moerke, Y.-H. Fan, H. Chen, W. J. Christ, G. Wagner , J. A. Halperin: Synthesis of fluorescein labeled 7-methylguanosinemonophosphate. Bioorg. Med. Chem. Lett., 14, 2657-2660 (2004).PMID: 15109672 Full Text

  5. M. Oberer, A. Marintchev, G. Wagner : Structural basis for the enhancement of eIF4A helicase activity by eIF4G, Genes & Development, 19, 2212-2223 (2005). PMID: 16166382 Full Text

  6. A. Marintchev, G. Wagner : eIF4G and CBP80 share a common origin and similar domain organization - implications for the eIF4G structure and function, Biochemistry, 44, 12265-12272 (2005). PMID: 16156639 Full Text

  7. M.-E. Bordeleau, A. Mori, M. Oberer, L. Lindqvist, L. S Chard, T. Higa, G. J Belsham, G. Wagner, J. Tanaka & J. Pelletier: Functional characterization of IRESes by an inhibitor of the RNA helicase eIF4A, Nat. Chem. Biol., 2, 213-220 (2006). PMID: 16532013 Full Text

  8. Vladimir Gelev, Husseyin Aktas, Assen Marintchev, Takuhiro Ito, Dominique Frueh, Michael Hemond, David Rovnyak, Miriam Debus, Sven Hyberts, Anny Usheva, Jose Halperin and Gerhard Wagner: Mapping of the Auto-Inhibitory Interactions of Protein Kinase R by Nuclear Magnetic Resonance, J. Mol. Biol., 364, 352-363 (2006). PMID: 17011579 Full Text

  9. Bordeleau ME, Cencic R, Lindqvist L, Oberer M, Northcote P, Wagner G, Pelletier J.: RNA-Mediated Sequestration of the RNA Helicase eIF4A by Pateamine A Inhibits Translation Initiation. Chem Biol. 13, 1287-95 (2006). PMID: 17185224 Full Text